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Pathologica 2 by Andrew Plotkin is an experimental tabletop role-playing game that simulates a plague outbreak in the 1920's Russia caused by bacterium "Yersinia Pestis." Players take on roles as members of various classes such to survive and cope with the chaos, including doctors who can cure Plague victims through medication or prayer. The gameplay involves rolling dice for actions during each turn while avoiding contracting diseases from infected patients at a cost; resources are scarce in this world where many have been killed by "Pestis."